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Index > Protein center > Impa1(Gene name) > Mouse
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  • Impa1 (Gene name),
  • Inositol monophosphatase 1 (Protein name ),  IMPA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Impa1;
    Protein name:
    Inositol monophosphatase 1(IMP 1;IMPase 1);
    Alternative:
    Lithium-sensitive myo-inositol monophosphatase A1;Inositol-1(or 4)-monophosphatase 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MADPWQECMD | YAVILARQAG | EMIREALKNE | MDVMIKSSPA | DLVTVTDQKV | 
    100:
    EKMLMSSIKE | KYPCHSFIGE | ESVAAGEKTV | FTESPTWFID | PIDGTTNFVH | 
    150:
    RFPFVAVSIG | FLVNKEMEFG | IVYSCVEDKM | YTGRKGKGAF | CNGQKLQVSQ | 
    200:
    QEDITKSLLV | TELGSSRKPE | TLRIVLSNME | KLCSIPIHGI | RSVGTAAVNM | 
    250:
    CLVATGGADA | YYEMGIHCWD | MAGAGIIVTE | AGGVLMDVTG | GPFDLMSRRI | 
    277:
    IAANSITLAK | RIAKEIEIIP | LQRDDES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IMP 1
    Cat.:
    E1404h
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    96T
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    ELISA Kit for Mouse IMP 1
    Cat.:
    E1404b
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    96T
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    ELISA Kit for Mouse IMP 1
    Cat.:
    E1404p
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    96T
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    ELISA Kit for Mouse IMP 1
    Cat.:
    E1404r
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    96T
    ELISA Kit for Mouse IMP 1
    Cat.:
    E1404m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse IMP 1
    Cat.:
    U1404r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse IMP 1
    Cat.:
    U1404b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IMP 1
    Cat.:
    U1404p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IMP 1
    Cat.:
    U1404h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IMP 1
    Cat.:
    U1404m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse IMP 1
    Cat.:
    P1404Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IMP 1
    Cat.:
    P1404Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IMP 1
    Cat.:
    P1404Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IMP 1
    Polyclonal Antibody for Mouse IMP 1
    Monoclonal Antibody for Mouse IMP 1
    Monoclonal Antibody for Mouse IMP 1
    Monoclonal Antibody for Mouse IMP 1
    Monoclonal Antibody for Mouse IMP 1
    Monoclonal Antibody for Mouse IMP 1
    Protein for Mouse IMP 1
    Protein for Mouse IMP 1
    Protein for Mouse IMP 1
    Protein for Mouse IMP 1
    Protein for Mouse IMP 1

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    References
    1. 1.
      Parthasarathy L. , Parthasarathy R. , Vadnal R.E.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The effect of lithium on expression of genes for inositol biosynthetic enzymes in mouse hippocampus; a comparison with the yeast model."
      Shamir A. , Shaltiel G. , Greenberg M.L. , Belmaker R.H. , Agam G.
      Brain Res. Mol. Brain Res.115:104-110(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    3. 3.
      "Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1."
      Ohnishi T. , Ohba H. , Seo K.-C. , Im J. , Sato Y. , Iwayama Y. , Furuichi T. , Chung S.-K. , Yoshikawa T.
      J. Biol. Chem.282:637-646(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      "Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens."
      Singh N. , Halliday A.C. , Knight M. , Lack N.A. , Lowe E. , Churchill G.C.
      Acta Crystallogr. F68:1149-1152(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.43 ANGSTROMS) IN COMPLEX WITH MAGNESIUM AND PHOSPHATE;SUBUNIT;COFACTOR
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